Preparation of pellets containing highly soluble drug by extrusion/spheronisation and coating with Kollicoat® SR 30D
نویسندگان
چکیده
منابع مشابه
Comparative Study of Aqueous Dispersion of Different Types of Polymers on Release Behavior of Salbutamol Sulphate from Coated Pellets
The present study was designed to investigate the effect of different types of coating polymers such as Eudragit RL 30D, Eudragit RS 30D, Eudragit NE 30D, Surelease, and Kollicoat SR 30D on physical properties and release pattern of salbutamol sulphate (SS) pellets which were prepared by Extrusion-Spheronization technology. All the polymers used in coating solution were in aqueous dispersion fo...
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In this study different sized sustained-release coated pellets (6, 2.5 and 1 mm in diameter) were investigated using terahertz pulsed imaging (TPI). Ten pellets from each batch of metoprolol succinate layered sugar starter cores coated with a 75:25 (w/w) polymer blend of Kollicoat SR and Kollicoat IR (approximate coating thickness of 60 μm, according to the weight gain) were mapped individually...
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Pellets containing theophylline as a model drug and microcrystalline cellulose, in a ratio of 6:4, were prepared by the extrusion-spheronization method. The pellets were coated with Eudragit RS aqueous dispersions, containing various amounts of pectin-chitosan complex and different coating mass gains, using a fluidized-bed apparatus. Twelve formulations were developed, which differed in two fac...
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Since the use of PEG-coated pellets for the first oral sustainedrelease formulation in 1952, coated pellets have been used extensively to control the drug release kinetics. The term “pellet” has been used interchangeably with other terms, such as bead, sphere, granule, and particle. A large number of drug products have been available to patients. Despite extensive use of the coated pellets, the...
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هدف از این تحقیق بررسی برخی عوامل ادراکی واحساسی یعنی استفاده از شیوه های یادگیری زبان ، انگیزه ها ونگرش نسبت به زبان انگلیسی در رابطه با زمینه زبانی زبان آموزان می باشد. هدف بررسی این نکته بود که آیا اختلافی چشمگیر میان زبان آموزان دو زبانه و تک زبانه در میزان استفاده از شیوه های یادگیری زبان ، انگیزه ها نگرش و سطح مهارت زبانی وجود دارد. همچنین سعی شد تا بهترین و موثرترین عوامل پیش بینی کننده ...
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ژورنال
عنوان ژورنال: Brazilian Archives of Biology and Technology
سال: 2011
ISSN: 1516-8913
DOI: 10.1590/s1516-89132011000200013